SELECTED Publications



  • Pancreas organogenesis: The interplay between surrounding microenvironment(s) and epithelium-intrinsic factors. Cozzitorto C, Spagnoli FM. Current Topics in Developmental Biology. 2019 [Link to publication]


  • Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors. Escot S, Willnow D, Naumann H, Di Francescantonio S, Spagnoli FM. Nature Communications. 2018 9(1):5082. doi: 10.1038/s41467-018-07474-6. PMID: 30504829 [PubMed]

  • Location matters for insulin-producing cells. Spagnoli FM. Nature. 2018 564(7734):50-51. doi: 10.1038/d41586-018-07490-y. Invited editorial. PMID: 30510228 [PubMed]

  • The RhoGAP Stard13 controls insulin secretion through F-actin remodeling. Naumann, H., Rathjen, T., Poy, MN., Spagnoli, F.M. Molecular Metabolism. 2018 8:96-105. doi: 10.1016/j.molmet.2017.12.013. PMID: 29310936 [PubMed]

  • Step-wise reprogramming of liver to pancreas progenitor state by the transcriptional regulator Tgif2. Cerdá-Esteban N, Naumann N, Ruzzittu S, Cozzitorto C, Pongrac IM, Hommel A, Mah N, Andrade-Navarro MA, Bonifacio E, Spagnoli FM. Nature Communications. 2017 8:14127. doi:10.1038/ncomms14127. PMID: 28193997 [PubMed]

  • Setd7 is a regulator of pancreatic cell identity. Kofent J, Zhang J, Spagnoli FM. Development. 2016 143(19):3573-3581.

  • Xenopus as a model system for studying pancreatic development and diabetes. Kofent J, Spagnoli FM. Semin Cell Dev Biol. 2016 Mar;51:106-16. Invited Review. PMID: 26806634 [PubMed]

  • In vivo reprogramming for tissue repair: Recent breakthroughs and future challenges. Heinrich C, Spagnoli FM*, Berninger B*. Nature Cell Biology. 2015 17(3):204-11. Invited Review. *co-corresponding authors.

  • Recessive mutations in PCBD1 gene cause a new type of early-onset diabetes. Simaite D, Kofent J*, Gong M, Ruschendorf F, Jia S, Arn P, Bentler K, Ellaway C,Kuehnen P, Hoffmann GK, Blau N, Spagnoli FM, Huebner N, Raile K. Diabetes. 2014 63:3557-64. *second author was a student in my laboratory. PMID: 24848070 [PubMed]

  • Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence. Rodríguez-Seguel E, Mah N, Naumann H, Pongrac IM, Cerdá-Esteban N, Fontaine JF, Wang Y, Chen W, Andrade-Navarro MA, Spagnoli FM. Genes & Development. 2013 27(17):1932-46. PMID: 24013505 [PubMed]

  • Glimpse into Hox and Tale regulation of cell differentiation and reprogramming. Cerdá-Esteban N, Spagnoli FM. Dev. Dyn. 2014 243(1):76-87. Invited review. PMID: 24123411 [PubMed]

  • Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. Petzold KM, Naumann H, Spagnoli FM. Development. 2013 140(1):126-35. PMID: 23175628 [PubMed]

  • A system for ex vivo culturing of embryonic pancreas. Petzold KM, Spagnoli FM. J Vis Exp. 2012 Aug 27;(66):e3979. doi: 10.3791/3979. PMID: 22951988 [PubMed]

  • The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection. Spagnoli FM*, Rosa A*, Brivanlou AH. Developmental Cell. 2009 Apr;16(4):517-27. *co-first authors (Faculty 1000). PMID: 19386261 [PubMed]

  • The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm. Spagnoli FM, Brivanlou AH. Development. 2008 Feb;135(3):451-61. PMID:  18094028 [PubMed]

  • Balancing BMP signaling through integrated inputs into the Smad1 linker. Sapkota G, Alarcón C, Spagnoli FM, Brivanlou AH, Massagué J. Mol Cell. 2007 Feb 9;25(3):441-54. PMID: 17289590 [PubMed]